The game plot reminds several recent Hollywood comedies at once. The U.S. Drug Enforcement gets Ramiro Cruz out of prison, and tells him two pieces of news. The first is that his twin brother, who used to work undercover in Mexico, lost his hand after the "accident" with a grenade . 第二，拉米羅將佔據他兄弟的位置，繼續在邪惡的毒梟Papa Muerte後方進行顛覆活動，同時找到並懲罰他父親的兇手。
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